Genotypic Stability of Cold-Adapted Influenza Virus Vaccine in an Efficacy Clinical Trial
نویسندگان
چکیده
منابع مشابه
Genotypic stability of cold-adapted influenza virus vaccine in an efficacy clinical trial.
An investigational live influenza virus vaccine, FluMist, contains three cold-adapted H1N1, H3N2, and B influenza viruses. The vaccine viruses are 6/2 reassortants, in which the hemagglutinin (HA) and neuraminidase (NA) genes are derived from the circulating wild-type viruses and the remaining six genes are derived from the cold-adapted master donor strains. The six genes from the cold-adapted ...
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ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 2000
ISSN: 0095-1137,1098-660X
DOI: 10.1128/jcm.38.2.839-845.2000